Cargando…

Synergistic Effect of Retinoic Acid Polymeric Micelles and Prodrug for the Pharmacodynamic Evaluation of Tumor Suppression

All-trans retinoic acid (ATRA) is an effective agent that induces differentiation, inhibits cell proliferation, and acts as an anticancer agent. ATRA was successfully conjugated with Pluronic F127 via esterification to enhance its anticancer effects. Pluronic-ATRA showed high cytotoxicity and inhibi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Yan-Hua, Ye, Ning, Tang, Xin-Feng, Khan, Malik Ihsanullah, Liu, Hong-Liang, Shi, Ning, Hang, Li-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531846/
https://www.ncbi.nlm.nih.gov/pubmed/31156425
http://dx.doi.org/10.3389/fphar.2019.00447