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Accelerated Deficits of Spatial Learning and Memory Resulting From Prenatal Inflammatory Insult Are Correlated With Abnormal Phosphorylation and Methylation of Histone 3 in CD-1 Mice

Gestational infection causes various neurological deficits in offspring, such as age-related spatial learning and memory (SLM) decline. How inflammation causes age-related SLM dysfunction remains unknown. Previous research has indicated that histone modifications, such as phosphorylation of H3S10 (H...

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Detalles Bibliográficos
Autores principales: Wu, Zi-Xing, Cao, Lei, Li, Xue-Wei, Jiang, Wei, Li, Xue-Yan, Xu, Jing, Wang, Fang, Chen, Gui-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531990/
https://www.ncbi.nlm.nih.gov/pubmed/31156421
http://dx.doi.org/10.3389/fnagi.2019.00114