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Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats and non-human primates

BACKGROUND: Recurrent and persistent infections are known to affect airways of patients with Primary Immunodeficiency despite appropriate replacement immunoglobulin serum levels. Interestingly, patients with Chronic Obstructive Pulmonary Disease or with non-CF bronchiectasis also show similar suscep...

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Detalles Bibliográficos
Autores principales: Vonarburg, Cédric, Loetscher, Marius, Spycher, Martin O., Kropf, Alain, Illi, Marlies, Salmon, Sharon, Roberts, Sean, Steinfuehrer, Karin, Campbell, Ian, Koernig, Sandra, Bain, Joseph, Edler, Monika, Baumann, Ulrich, Miescher, Sylvia, Metzger, Dennis W., Schaub, Alexander, Käsermann, Fabian, Zuercher, Adrian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532128/
https://www.ncbi.nlm.nih.gov/pubmed/31118031
http://dx.doi.org/10.1186/s12931-019-1057-3