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Lamin A/C and Emerin depletion impacts chromatin organization and dynamics in the interphase nucleus

BACKGROUND: Nuclear lamins are type V intermediate filament proteins that maintain nuclear structure and function. Furthermore, Emerin - an interactor of Lamin A/C, facilitates crosstalk between the cytoskeleton and the nucleus as it also interacts with actin and Nuclear Myosin 1 (NM1). RESULTS: Her...

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Detalles Bibliográficos
Autores principales: Ranade, Devika, Pradhan, Roopali, Jayakrishnan, Muhunden, Hegde, Sushmitha, Sengupta, Kundan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532135/
https://www.ncbi.nlm.nih.gov/pubmed/31117946
http://dx.doi.org/10.1186/s12860-019-0192-5