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Natural killer cells and pigment epithelial-derived factor control the infiltrative and nodular growth of hepatic metastases in an Orthotopic murine model of ocular melanoma

BACKGROUND: Metastases account for 90% of all cancer-related deaths, becoming a therapeutic problem. Approximately 50% of all uveal melanoma (UM) patients will develop metastases, mainly in the liver. Post-mortem analyses of livers from metastatic UM patients showed two different metastatic growth p...

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Detalles Bibliográficos
Autores principales: Jones, Nyasia M., Yang, Hua, Zhang, Qing, Morales-Tirado, Vanessa M., Grossniklaus, Hans E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532210/
https://www.ncbi.nlm.nih.gov/pubmed/31117965
http://dx.doi.org/10.1186/s12885-019-5712-3