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Integrated high-throughput analysis identifies super enhancers associated with chemoresistance in SCLC
BACKGROUND: Chemoresistance is a primary clinical challenge for the management of small cell lung cancer. Additionally, transcriptional regulation by super enhancer (SE) has an important role in tumor evolution. The functions of SEs, a key class of noncoding DNA cis-regulatory elements, have been th...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532255/ https://www.ncbi.nlm.nih.gov/pubmed/31118037 http://dx.doi.org/10.1186/s12920-019-0520-9 |