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Integrated high-throughput analysis identifies super enhancers associated with chemoresistance in SCLC

BACKGROUND: Chemoresistance is a primary clinical challenge for the management of small cell lung cancer. Additionally, transcriptional regulation by super enhancer (SE) has an important role in tumor evolution. The functions of SEs, a key class of noncoding DNA cis-regulatory elements, have been th...

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Detalles Bibliográficos
Autores principales:	Bao, Jiarong, Li, Man, Liang, Shumei, Yang, Yunchu, Wu, Jingfang, Zou, Qingqing, Fang, Shun, Chen, Size, Guo, Linlang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532255/ https://www.ncbi.nlm.nih.gov/pubmed/31118037 http://dx.doi.org/10.1186/s12920-019-0520-9

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