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Human Immune System Increases Breast Cancer-Induced Osteoblastic Bone Growth in a Humanized Mouse Model without Affecting Normal Bone

Bone metastases are prevalent in many common cancers such as breast, prostate, and lung cancers, and novel therapies for treating bone metastases are needed. Human immune system-engrafted models are used in immuno-oncology (IO) studies for subcutaneous cancer cell or patient-derived xenograft implan...

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Detalles Bibliográficos
Autores principales: Kähkönen, Tiina E., Suominen, Mari I., Mäki-Jouppila, Jenni H. E., Halleen, Jussi M., Tanaka, Azusa, Seiler, Michael, Bernoulli, Jenni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532310/
https://www.ncbi.nlm.nih.gov/pubmed/31211147
http://dx.doi.org/10.1155/2019/4260987