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Simplified immunosuppressive and neuroprotective agents based on gracilin A
The architecture and bioactivity of natural products frequently serves as an embarkation point for exploration of biologically-relevant chemical space. Total synthesis followed by derivative synthesis has historically enabled a deeper understanding of structure-activity relationships. However, synth...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532426/ https://www.ncbi.nlm.nih.gov/pubmed/30903037 http://dx.doi.org/10.1038/s41557-019-0230-0 |