The Extent of Human Apolipoprotein A-I Lipidation Strongly Affects the β-Amyloid Efflux Across the Blood-Brain Barrier in vitro

Much evidence suggests a protective role of high-density lipoprotein (HDL) and its major apolipoprotein apoA-I, in Alzheimer’s disease (AD). The biogenesis of nascent HDL derived from a first lipidation of apoA-I, which is synthesized by the liver and intestine but not in the brain, in a process med...

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Detalles Bibliográficos
Autores principales: Dal Magro, Roberta, Simonelli, Sara, Cox, Alysia, Formicola, Beatrice, Corti, Roberta, Cassina, Valeria, Nardo, Luca, Mantegazza, Francesco, Salerno, Domenico, Grasso, Gianvito, Deriu, Marco Agostino, Danani, Andrea, Calabresi, Laura, Re, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532439/
https://www.ncbi.nlm.nih.gov/pubmed/31156358
http://dx.doi.org/10.3389/fnins.2019.00419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532439/
https://www.ncbi.nlm.nih.gov/pubmed/31156358
http://dx.doi.org/10.3389/fnins.2019.00419

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