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Embelin, a Potent Molecule for Alzheimer's Disease: A Proof of Concept From Blood-Brain Barrier Permeability, Acetylcholinesterase Inhibition and Molecular Docking Studies

Embelin is well-known in ethnomedicine and reported to have central nervous system activities. However, there is no report on blood-brain barrier (BBB) permeability of embelin. Here the BBB permeability of embelin was evaluated using in vitro primary porcine brain endothelial cell (PBEC) model of th...

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Detalles Bibliográficos
Autores principales: Bhuvanendran, Saatheeyavaane, Hanapi, Nur Aziah, Ahemad, Nafees, Othman, Iekhsan, Yusof, Siti Rafidah, Shaikh, Mohd Farooq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532548/
https://www.ncbi.nlm.nih.gov/pubmed/31156375
http://dx.doi.org/10.3389/fnins.2019.00495