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Scrodentoid A Inhibits Mast Cell–Mediated Allergic Response by Blocking the Lyn–FcεRIβ Interaction

Background: Mast cells are considered an attractive therapeutic target for treating allergic diseases, and the Lyn–FcεRIβ interaction is essential for mast cell activation. This study investigated the antiallergic effect of scrodentoid A (SA) on mast cells and mast cell–mediated anaphylaxis. Methods...

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Detalles Bibliográficos
Autores principales: Qian, Fei, Zhang, Liuqiang, Lu, Shaodong, Mao, Gaohui, Guo, Fujiang, Liu, Ping, Xu, Jinwen, Li, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532554/
https://www.ncbi.nlm.nih.gov/pubmed/31156646
http://dx.doi.org/10.3389/fimmu.2019.01103