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Structure-Activity Relationship Analysis of YM155 for Inducing Selective Cell Death of Human Pluripotent Stem Cells

Despite great potential for regenerative medicine, the high tumorigenic potential of human pluripotent stem cells (hPSCs) to form undesirable teratoma is an important technical hurdle preventing safe cell therapy. Various small molecules that induce the complete elimination of undifferentiated hPSCs...

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Detalles Bibliográficos
Autores principales: Go, Young-Hyun, Lim, Changjin, Jeong, Ho-Chang, Kwon, Ok-Seon, Chung, Sungkyun, Lee, Haeseung, Kim, Wankyu, Suh, Young-Ger, Son, Woo Sung, Lee, Mi-Ok, Cha, Hyuk-Jin, Kim, Seok-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532689/
https://www.ncbi.nlm.nih.gov/pubmed/31157201
http://dx.doi.org/10.3389/fchem.2019.00298