MMP14-Containing Exosomes Cleave VEGFR1 and Promote VEGFA-Induced Migration and Proliferation of Vascular Endothelial Cells

PURPOSE: Investigate the impact matrix metalloproteinase 14 (MMP14) delivered via exosomes produced by corneal fibroblasts on vascular endothelial growth factor receptor 1 (VEGFR1) cleavage on endothelial cells, and other key processes of angiogenesis. METHODS: Proteolysis of VEGFR1 and R2 by the ca...

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Detalles Bibliográficos
Autores principales: Han, Kyu-Yeon, Chang, Jin-Hong, Azar, Dimitri T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532701/
https://www.ncbi.nlm.nih.gov/pubmed/31117124
http://dx.doi.org/10.1167/iovs.18-26277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532701/
https://www.ncbi.nlm.nih.gov/pubmed/31117124
http://dx.doi.org/10.1167/iovs.18-26277

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