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MMP14-Containing Exosomes Cleave VEGFR1 and Promote VEGFA-Induced Migration and Proliferation of Vascular Endothelial Cells

PURPOSE: Investigate the impact matrix metalloproteinase 14 (MMP14) delivered via exosomes produced by corneal fibroblasts on vascular endothelial growth factor receptor 1 (VEGFR1) cleavage on endothelial cells, and other key processes of angiogenesis. METHODS: Proteolysis of VEGFR1 and R2 by the ca...

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Detalles Bibliográficos
Autores principales:	Han, Kyu-Yeon, Chang, Jin-Hong, Azar, Dimitri T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2019
Materias:	Cornea
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532701/ https://www.ncbi.nlm.nih.gov/pubmed/31117124 http://dx.doi.org/10.1167/iovs.18-26277

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