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Computational study on new natural compound agonists of stimulator of interferon genes (STING)

OBJECTIVE: This study aimed to screen lead compounds and medication candidates from drug library (ZINC database) which has potential agonist effect targeting STING protein. METHODS AND MATERIALS: A series of computer-aided virtual screening techniques were utilized to identify potential agonists of...

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Detalles Bibliográficos
Autores principales: Zhong, Sheng, Li, Weihang, Bai, Yang, Wu, Bo, Wang, Xinhui, Jiang, Shanshan, Zhao, Yingjing, Ren, Jiaxin, Li, Hui, Jin, Rihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532845/
https://www.ncbi.nlm.nih.gov/pubmed/31120925
http://dx.doi.org/10.1371/journal.pone.0216678