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Metabolic, mitochondrial, renal and hepatic safety of enfuvirtide and raltegravir antiretroviral administration: Randomized crossover clinical trial in healthy volunteers

CONTEXT: Classical antiretroviral agents may acutely impact on metabolic, mitochondrial, renal and hepatic function in HIV-infected and uninfected persons. Fusion and integrase inhibitors are supposed to be safer, but have been scarcely investigated. To avoid any interference with HIV or other antir...

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Detalles Bibliográficos
Autores principales: Barroso, Sergio, Morén, Constanza, González-Segura, Àlex, Riba, Neus, Arnaiz, Joan A., Manriquez, Marcela, Santana, Gemina, Blanco, José L., Larousse, María, Loncà, Montse, de Lazzari, Elisa, Llopis, Jaume, Mallolas, Josep, Miró, Oscar, Carné, Xavier, Gatell, Jose M., Garrabou, Glòria, Martínez, Esteban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532851/
https://www.ncbi.nlm.nih.gov/pubmed/31120908
http://dx.doi.org/10.1371/journal.pone.0216712