Norcantharidin regulates ERα signaling and tamoxifen resistance via targeting miR-873/CDK3 in breast cancer cells

MiR-873/CDK3 has been shown to play a critical role in ERα signaling and tamoxifen resistance. Thus, targeting this pathway may be a potential therapeutic approach for the treatment of ER positive breast cancer especially tamoxifen resistant subtype. Here we report that Norcantharidin (NCTD), curren...

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Detalles Bibliográficos
Autores principales: Zhang, Xiumei, Zhang, Bingfeng, Zhang, Panhong, Lian, Lihui, Li, Lianlian, Qiu, Zhihong, Qian, Kai, Chen, An, Liu, Qiongqing, Jiang, Yinjie, Cui, Jiajun, Qi, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532885/
https://www.ncbi.nlm.nih.gov/pubmed/31120927
http://dx.doi.org/10.1371/journal.pone.0217181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532885/
https://www.ncbi.nlm.nih.gov/pubmed/31120927
http://dx.doi.org/10.1371/journal.pone.0217181

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