Sir2 suppresses transcription-mediated displacement of Mcm2-7 replicative helicases at the ribosomal DNA repeats

Repetitive DNA sequences within eukaryotic heterochromatin are poorly transcribed and replicate late in S-phase. In Saccharomyces cerevisiae, the histone deacetylase Sir2 is required for both transcriptional silencing and late replication at the repetitive ribosomal DNA arrays (rDNA). Despite the wi...

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Detalles Bibliográficos
Autores principales: Foss, Eric J., Gatbonton-Schwager, Tonibelle, Thiesen, Adam H., Taylor, Erin, Soriano, Rafael, Lao, Uyen, MacAlpine, David M., Bedalov, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532929/
https://www.ncbi.nlm.nih.gov/pubmed/31083663
http://dx.doi.org/10.1371/journal.pgen.1008138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532929/
https://www.ncbi.nlm.nih.gov/pubmed/31083663
http://dx.doi.org/10.1371/journal.pgen.1008138

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