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Enhanced flux prediction by integrating relative expression and relative metabolite abundance into thermodynamically consistent metabolic models
The ever-increasing availability of transcriptomic and metabolomic data can be used to deeply analyze and make ever-expanding predictions about biological processes, as changes in the reaction fluxes through genome-wide pathways can now be tracked. Currently, constraint-based metabolic modeling appr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532942/ https://www.ncbi.nlm.nih.gov/pubmed/31083653 http://dx.doi.org/10.1371/journal.pcbi.1007036 |