Cargando…
Enhanced flux prediction by integrating relative expression and relative metabolite abundance into thermodynamically consistent metabolic models
The ever-increasing availability of transcriptomic and metabolomic data can be used to deeply analyze and make ever-expanding predictions about biological processes, as changes in the reaction fluxes through genome-wide pathways can now be tracked. Currently, constraint-based metabolic modeling appr...
Autores principales: | Pandey, Vikash, Hadadi, Noushin, Hatzimanikatis, Vassily |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532942/ https://www.ncbi.nlm.nih.gov/pubmed/31083653 http://dx.doi.org/10.1371/journal.pcbi.1007036 |
Ejemplares similares
-
The ETFL formulation allows multi-omics integration in thermodynamics-compliant metabolism and expression models
por: Salvy, Pierre, et al.
Publicado: (2020) -
Investigating the deregulation of metabolic tasks via Minimum Network Enrichment Analysis (MiNEA) as applied to nonalcoholic fatty liver disease using mouse and human omics data
por: Pandey, Vikash, et al.
Publicado: (2019) -
NICEdrug.ch, a workflow for rational drug design and systems-level analysis of drug metabolism
por: MohammadiPeyhani, Homa, et al.
Publicado: (2021) -
Enzyme annotation for orphan and novel reactions using knowledge of substrate reactive sites
por: Hadadi, Noushin, et al.
Publicado: (2019) -
A genome-scale metabolic model of Saccharomyces cerevisiae that integrates expression constraints and reaction thermodynamics
por: Oftadeh, Omid, et al.
Publicado: (2021)