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The ability of transcription factors to differentially regulate gene expression is a crucial component of the mechanism underlying inversion, a frequently observed genetic interaction pattern

Genetic interactions, a phenomenon whereby combinations of mutations lead to unexpected effects, reflect how cellular processes are wired and play an important role in complex genetic diseases. Understanding the molecular basis of genetic interactions is crucial for deciphering pathway organization...

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Detalles Bibliográficos
Autores principales: Amini, Saman, Jacobsen, Annika, Ivanova, Olga, Lijnzaad, Philip, Heringa, Jaap, Holstege, Frank C. P., Feenstra, K. Anton, Kemmeren, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532943/
https://www.ncbi.nlm.nih.gov/pubmed/31083661
http://dx.doi.org/10.1371/journal.pcbi.1007061