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The R2TP complex regulates paramyxovirus RNA synthesis

The regulation of paramyxovirus RNA synthesis by host proteins is poorly understood. Here, we identified a novel regulation mechanism of paramyxovirus RNA synthesis by the Hsp90 co-chaperone R2TP complex. We showed that the R2TP complex interacted with the paramyxovirus polymerase L protein and that...

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Detalles Bibliográficos
Autores principales: Katoh, Hiroshi, Sekizuka, Tsuyoshi, Nakatsu, Yuichiro, Nakagawa, Reiko, Nao, Naganori, Sakata, Masafumi, Kato, Fumihiro, Kuroda, Makoto, Kidokoro, Minoru, Takeda, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532945/
https://www.ncbi.nlm.nih.gov/pubmed/31121004
http://dx.doi.org/10.1371/journal.ppat.1007749