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Macrophage subsets exhibit distinct E. coli-LPS tolerisable cytokines associated with the negative regulators, IRAK-M and Tollip

Macrophages (Mϕs) play a central role in mucosal immunity by pathogen sensing and instruction of adaptive immune responses. Prior challenge to endotoxin can render Mφs refractory to secondary exposure, suppressing the inflammatory response. Previous studies demonstrated a differential subset-specifi...

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Detalles Bibliográficos
Autores principales: Al-Shaghdali, Khalid, Durante, Barbara, Hayward, Christopher, Beal, Jane, Foey, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533032/
https://www.ncbi.nlm.nih.gov/pubmed/31120887
http://dx.doi.org/10.1371/journal.pone.0214681