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Human macular Müller cells rely more on serine biosynthesis to combat oxidative stress than those from the periphery

The human macula is more susceptible than the peripheral retina to developing blinding conditions such as age-related macular degeneration, diabetic retinopathy. A key difference between them may be the nature of their Müller cells. We found primary cultured Müller cells from macula and peripheral r...

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Detalles Bibliográficos
Autores principales: Zhang, Ting, Zhu, Ling, Madigan, Michele C, Liu, Wei, Shen, Weiyong, Cherepanoff, Svetlana, Zhou, Fanfan, Zeng, Shaoxue, Du, Jianhai, Gillies, Mark C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533082/
https://www.ncbi.nlm.nih.gov/pubmed/31036157
http://dx.doi.org/10.7554/eLife.43598