Epigenetic evolution and lineage histories of chronic lymphocytic leukemia

Genetic and epigenetic intra-tumoral heterogeneity cooperate to shape the evolutionary course of cancer(1). Chronic lymphocytic leukemia (CLL) is a highly informative model for cancer evolution as it undergoes substantial genetic diversification and evolution with therapy(2,3). The CLL epigenome is...

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Detalles Bibliográficos
Autores principales: Gaiti, Federico, Chaligne, Ronan, Gu, Hongcang, Brand, Ryan Matthew, Kothen-Hill, Steven, Schulman, Rafael, Grigorev, Kirill, Risso, Davide, Kim, Kyu-Tae, Pastore, Alessandro, Huang, Kevin Y., Alonso, Alicia, Sheridan, Caroline, Omans, Nathaniel D., Biederstedt, Evan, Clement, Kendell, Wang, Lili, Felsenfeld, Joshua A., Bhavsar, Erica B., Aryee, Martin J., Allan, John N., Furman, Richard, Gnirke, Andreas, Wu, Catherine J., Meissner, Alexander, Landau, Dan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533116/
https://www.ncbi.nlm.nih.gov/pubmed/31092926
http://dx.doi.org/10.1038/s41586-019-1198-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533116/
https://www.ncbi.nlm.nih.gov/pubmed/31092926
http://dx.doi.org/10.1038/s41586-019-1198-z

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