The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template

Epitope-targeted HIV vaccine design seeks to focus antibody responses to broadly neutralizing antibody (bnAb) sites by sequential immunization. A chimpanzee simian immunodeficiency virus (SIV) envelope (Env) shares a single bnAb site, the variable loop 2 (V2)-apex, with HIV, suggesting its possible...

Descripción completa

Detalles Bibliográficos
Autores principales: Andrabi, Raiees, Pallesen, Jesper, Allen, Joel D., Song, Ge, Zhang, Jinsong, de Val, Natalia, Gegg, Gavin, Porter, Katelyn, Su, Ching-Yao, Pauthner, Matthias, Newman, Amanda, Bouton-Verville, Hilary, Garces, Fernando, Wilson, Ian A., Crispin, Max, Hahn, Beatrice H., Haynes, Barton F., Verkoczy, Laurent, Ward, Andrew B., Burton, Dennis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533203/
https://www.ncbi.nlm.nih.gov/pubmed/31116986
http://dx.doi.org/10.1016/j.celrep.2019.04.082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533203/
https://www.ncbi.nlm.nih.gov/pubmed/31116986
http://dx.doi.org/10.1016/j.celrep.2019.04.082

Ejemplares similares