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Germline TP53 mutation spectrum in Sudanese premenopausal breast cancer patients: correlations with reproductive factors

PURPOSE: The role of non-genetic factors as modifiers of TP53-related hereditary breast cancer (BC) risk is debated. In this regard, little is known about the impact of germline TP53 mutations on BC in sub-Saharan Africa, where the disease often presents in non-contraceptive multiparous premenopausa...

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Detalles Bibliográficos
Autores principales: Aceto, Gitana Maria, Awadelkarim, Khalid Dafaallah, Di Nicola, Marta, Moscatello, Carmelo, Pantalone, Mattia Russel, Verginelli, Fabio, Elwali, Nasr Eldin, Mariani-Costantini, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533225/
https://www.ncbi.nlm.nih.gov/pubmed/30796655
http://dx.doi.org/10.1007/s10549-019-05168-1