Sildenafil Reduces Neointimal Hyperplasia after Angioplasty and Inhibits Platelet Aggregation via Activation of cGMP-dependent Protein Kinase

Sildenafil is known to reduce cardiac hypertrophy through cGMP-dependent protein kinase (cGK) activation. Studies have demonstrated that cGK has a central switching role in modulating vascular smooth muscle cell (VSMC) phenotype in response to vascular injury. Here, we aimed to examine the effects o...

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Detalles Bibliográficos
Autores principales: Yang, Han-Mo, Jin, Sooryeonhwa, Jang, Hyunduk, Kim, Ju-Young, Lee, Joo-Eun, Kim, Joonoh, Kim, Hyo-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533301/
https://www.ncbi.nlm.nih.gov/pubmed/31123275
http://dx.doi.org/10.1038/s41598-019-44190-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533301/
https://www.ncbi.nlm.nih.gov/pubmed/31123275
http://dx.doi.org/10.1038/s41598-019-44190-7

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