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Ras suppressor-1 (RSU-1) promotes cell invasion in aggressive glioma cells and inhibits it in non-aggressive cells through STAT6 phospho-regulation

Most gliomas are invasive tumors formed from glial cells and associated with high mortality rates. In this study, we characterized four glioma cell lines of varying degree of aggressiveness (H4, SW1088, A172 and U87-MG) in terms of morphology, cytoskeleton organization and stiffness, and evaluated t...

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Detalles Bibliográficos
Autores principales: Louca, Maria, Stylianou, Andreas, Minia, Angeliki, Pliaka, Vaia, Alexopoulos, Leonidas G., Gkretsi, Vasiliki, Stylianopoulos, Triantafyllos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533309/
https://www.ncbi.nlm.nih.gov/pubmed/31123330
http://dx.doi.org/10.1038/s41598-019-44200-8