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Mapping connections in signaling networks with ambiguous modularity

Modular Response Analysis (MRA) is a suite of methods that under certain assumptions permits the precise reconstruction of both the directions and strengths of connections between network modules from network responses to perturbations. Standard MRA assumes that modules are insulated, thereby neglec...

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Detalles Bibliográficos
Autores principales: Lill, Daniel, Rukhlenko, Oleksii S., Mc Elwee, Anthony James, Kashdan, Eugene, Timmer, Jens, Kholodenko, Boris N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533310/
https://www.ncbi.nlm.nih.gov/pubmed/31149348
http://dx.doi.org/10.1038/s41540-019-0096-1