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DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia

Mammalian spermatogenesis is sustained by mitotic germ cells with self-renewal potential known as undifferentiated spermatogonia. Maintenance of undifferentiated spermatogonia and spermatogenesis is dependent on tightly co-ordinated transcriptional and post-transcriptional mechanisms. The RNA helica...

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Detalles Bibliográficos
Autores principales: Legrand, Julien M. D., Chan, Ai-Leen, La, Hue M., Rossello, Fernando J., Änkö, Minna-Liisa, Fuller-Pace, Frances V., Hobbs, Robin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533336/
https://www.ncbi.nlm.nih.gov/pubmed/31123254
http://dx.doi.org/10.1038/s41467-019-09972-7