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The mechanical effects of CRT promoting autophagy via mitochondrial calcium uniporter down‐regulation and mitochondrial dynamics alteration

The mechanism of cardiac resynchronization therapy (CRT) remains unclear. In this study, mitochondria calcium uniporter (MCU), dynamin‐related protein‐1 (DNM1L/Drp1) and their relationship with autophagy in heart failure (HF) and CRT are investigated. Thirteen male beagle's dogs were divided in...

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Detalles Bibliográficos
Autores principales: Yu, Ziqing, Gong, Xue, Yu, Yong, Li, Minghui, Liang, Yixiu, Qin, Shengmei, Fulati, Zibire, Zhou, Nianwei, Shu, Xianhong, Nie, Zhenning, Dai, Shimo, Chen, Xueying, Wang, Jingfeng, Chen, Ruizhen, Su, Yangang, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533471/
https://www.ncbi.nlm.nih.gov/pubmed/30938090
http://dx.doi.org/10.1111/jcmm.14227