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Diversity of dermal fibroblasts as major determinant of variability in cell reprogramming

Induced pluripotent stem cells (iPSCs) are adult somatic cells genetically reprogrammed to an embryonic stem cell‐like state. Notwithstanding their autologous origin and their potential to differentiate towards cells of all three germ layers, iPSC reprogramming is still affected by low efficiency. A...

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Detalles Bibliográficos
Autores principales: Sacco, Anna Maria, Belviso, Immacolata, Romano, Veronica, Carfora, Antonia, Schonauer, Fabrizio, Nurzynska, Daria, Montagnani, Stefania, Di Meglio, Franca, Castaldo, Clotilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533477/
https://www.ncbi.nlm.nih.gov/pubmed/30980516
http://dx.doi.org/10.1111/jcmm.14316