Xanthatin inhibits STAT3 and NF‐κB signalling by covalently binding to JAK and IKK kinases

Aberrant activation of the signal transducer and activator of transcription 3 (STAT3) and the nuclear factor‐κB (NF‐κB) signalling pathways is associated with the development of cancer and inflammatory diseases. JAKs and IKKs are the key regulators in the STAT3 and NF‐κB signalling respectively. The...

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Detalles Bibliográficos
Autores principales: Liu, Man, Xiao, Cheng‐qian, Sun, Ming‐wei, Tan, Min‐jia, Hu, Li‐hong, Yu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533482/
https://www.ncbi.nlm.nih.gov/pubmed/30993883
http://dx.doi.org/10.1111/jcmm.14322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533482/
https://www.ncbi.nlm.nih.gov/pubmed/30993883
http://dx.doi.org/10.1111/jcmm.14322

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