Bridging adults and paediatrics with secondary hyperparathyroidism receiving haemodialysis: a pharmacokinetic‐pharmacodynamic analysis of cinacalcet

AIMS: The aims of this study were to develop a pharmacokinetic (PK) and PK‐pharmacodynamic (PK/PD) model of cinacalcet in adults and paediatrics with secondary hyperparathyroidism (SHPT) on dialysis, to test covariates of interest, and to perform simulations to inform dosing in paediatrics with SHPT...

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Detalles Bibliográficos
Autores principales: Chen, Ping, Sohn, Winnie, Narayanan, Adimoolam, Gisleskog, Per Olsson, Melhem, Murad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533487/
https://www.ncbi.nlm.nih.gov/pubmed/30756425
http://dx.doi.org/10.1111/bcp.13900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533487/
https://www.ncbi.nlm.nih.gov/pubmed/30756425
http://dx.doi.org/10.1111/bcp.13900

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