LncRNA KCNQ1OT1 enhanced the methotrexate resistance of colorectal cancer cells by regulating miR‐760/PPP1R1B via the cAMP signalling pathway

We aimed to explore the mechanism of the KCNQ1OT1/miR‐760/PPP1R1B axis acting to regulate methotrexate (MTX) resistance of colorectal cancer (CRC). Differentially expressed mRNAs and lncRNAs in MTX‐sensitive CRC cell lines and MTX‐resistant cell lines were determined through microarray analysis. App...

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Detalles Bibliográficos
Autores principales: Xian, Di, Zhao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533496/
https://www.ncbi.nlm.nih.gov/pubmed/30997746
http://dx.doi.org/10.1111/jcmm.14071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533496/
https://www.ncbi.nlm.nih.gov/pubmed/30997746
http://dx.doi.org/10.1111/jcmm.14071

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