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Isorhamnetin attenuates osteoarthritis by inhibiting osteoclastogenesis and protecting chondrocytes through modulating reactive oxygen species homeostasis

Increasing evidence indicates that osteoarthritis (OA) is a musculoskeletal disease affecting the whole joint, including both cartilage and subchondral bone. Reactive oxygen species (ROS) have been demonstrated to be one of the important destructive factors during early‐stage OA development. The obj...

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Detalles Bibliográficos
Autores principales: Zhou, Feng, Mei, Jingtian, Yuan, Kai, Han, Xiuguo, Qiao, Han, Tang, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533508/
https://www.ncbi.nlm.nih.gov/pubmed/30983153
http://dx.doi.org/10.1111/jcmm.14333