IRF3 and IRF7 mediate neovascularization via inflammatory cytokines

OBJECTIVE: To elucidate the role of interferon regulatory factor (IRF)3 and IRF7 in neovascularization. METHODS: Unilateral hind limb ischaemia was induced in Irf3(−/−), Irf7(−/−) and C57BL/6 mice by ligation of the left common femoral artery. Post‐ischaemic blood flow recovery in the paw was measur...

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Detalles Bibliográficos
Autores principales: Simons, Karin H., de Vries, Margreet R., de Jong, Rob C. M., Peters, Hendrika A. B., Jukema, J. Wouter, Quax, Paul H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533520/
https://www.ncbi.nlm.nih.gov/pubmed/30932349
http://dx.doi.org/10.1111/jcmm.14247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533520/
https://www.ncbi.nlm.nih.gov/pubmed/30932349
http://dx.doi.org/10.1111/jcmm.14247

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