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IRF3 and IRF7 mediate neovascularization via inflammatory cytokines
OBJECTIVE: To elucidate the role of interferon regulatory factor (IRF)3 and IRF7 in neovascularization. METHODS: Unilateral hind limb ischaemia was induced in Irf3(−/−), Irf7(−/−) and C57BL/6 mice by ligation of the left common femoral artery. Post‐ischaemic blood flow recovery in the paw was measur...
Autores principales: | Simons, Karin H., de Vries, Margreet R., de Jong, Rob C. M., Peters, Hendrika A. B., Jukema, J. Wouter, Quax, Paul H. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533520/ https://www.ncbi.nlm.nih.gov/pubmed/30932349 http://dx.doi.org/10.1111/jcmm.14247 |
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