Dysregulation of Mesenchymal Cell Survival Pathways in Severe Fibrotic Lung Disease: The Effect of Nintedanib Therapy

Impaired apoptotic clearance of myofibroblasts can result in the continuous expansion of scar tissue during the persistent injury in the lung. However, the molecular and cellular mechanisms underlying the apoptotic clearance of multiple mesenchymal cells including fibrocytes, fibroblasts and myofibr...

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Detalles Bibliográficos
Autores principales: Kasam, Rajesh K., Reddy, Geereddy B., Jegga, Anil G., Madala, Satish K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533541/
https://www.ncbi.nlm.nih.gov/pubmed/31156440
http://dx.doi.org/10.3389/fphar.2019.00532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533541/
https://www.ncbi.nlm.nih.gov/pubmed/31156440
http://dx.doi.org/10.3389/fphar.2019.00532

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