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Rutaecarpine prevents hypertensive cardiac hypertrophy involving the inhibition of Nox4‐ROS‐ADAM17 pathway

Rutaecarpine attenuates hypertensive cardiac hypertrophy in the rats with abdominal artery constriction (AAC); however, its mechanism of action remains largely unknown. Our previous study indicated that NADPH oxidase 4 (Nox4) promotes angiotensin II (Ang II)‐induced cardiac hypertrophy through the p...

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Detalles Bibliográficos
Autores principales: Zeng, Si‐yu, Yang, Li, Lu, Hui‐qin, Yan, Qiu‐jiang, Gao, Ling, Qin, Xu‐ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533562/
https://www.ncbi.nlm.nih.gov/pubmed/30953402
http://dx.doi.org/10.1111/jcmm.14308