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Estrogen receptor α-NOTCH1 axis enhances basal stem-like cells and epithelial-mesenchymal transition phenotypes in prostate cancer

BACKGROUND: Prostate cancer (PCa) is the second leading cause of mortality and a leading cause of malignant tumors in males. Prostate cancer stem cells (PCSCs) are likely the responsible cell types for cancer initiation, clinical treatment failure, tumor relapse, and metastasis. Estrogen receptor al...

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Detalles Bibliográficos
Autores principales: Shen, Yongmei, Cao, Jiasong, Liang, Zhixian, Lin, Qimei, Wang, Jianxi, Yang, Xu, Zhang, Ran, Zong, Jiaojiao, Du, Xiaoling, Peng, Yanfei, Zhang, Ju, Shi, Jiandang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533681/
https://www.ncbi.nlm.nih.gov/pubmed/31122254
http://dx.doi.org/10.1186/s12964-019-0367-x