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Statins significantly reduce mortality in patients receiving clopidogrel without affecting platelet activation and aggregation: a systematic review and meta-analysis

BACKGROUND: Combination of statins and clopidogrel is frequently administered in patients with coronary artery disease (CAD). They are mainly activated and eliminated in the liver by cytochrome P450 isoenzyme 3A4 (CYP3A4). The aim was to clarify whether the coadministration of clopidogrel and statin...

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Detalles Bibliográficos
Autores principales: An, Ke, Huang, Rong, Tian, Sai, Guo, Dan, Wang, Jiaqi, Lin, Hongyan, Wang, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533696/
https://www.ncbi.nlm.nih.gov/pubmed/31122249
http://dx.doi.org/10.1186/s12944-019-1053-0