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Statins significantly reduce mortality in patients receiving clopidogrel without affecting platelet activation and aggregation: a systematic review and meta-analysis
BACKGROUND: Combination of statins and clopidogrel is frequently administered in patients with coronary artery disease (CAD). They are mainly activated and eliminated in the liver by cytochrome P450 isoenzyme 3A4 (CYP3A4). The aim was to clarify whether the coadministration of clopidogrel and statin...
Autores principales: | An, Ke, Huang, Rong, Tian, Sai, Guo, Dan, Wang, Jiaqi, Lin, Hongyan, Wang, Shaohua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533696/ https://www.ncbi.nlm.nih.gov/pubmed/31122249 http://dx.doi.org/10.1186/s12944-019-1053-0 |
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