Inhibition of RNA polymerase III transcription by Triptolide attenuates colorectal tumorigenesis

BACKGROUND: Upregulation of RNA polymerase (Pol) III products, including tRNAs and 5S rRNA, in tumor cells leads to enhanced protein synthesis and tumor formation, making it a potential target for cancer treatment. In this study, we evaluated the inhibition of Pol III transcription by triptolide and...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Xia, Xie, Renxiang, Su, Jinfeng, Ye, Bingqi, Wei, Saisai, Liang, Zhibing, Bai, Rongpan, Chen, Zhanghui, Li, Zhongxiang, Gao, Xiangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533717/
https://www.ncbi.nlm.nih.gov/pubmed/31122284
http://dx.doi.org/10.1186/s13046-019-1232-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533717/
https://www.ncbi.nlm.nih.gov/pubmed/31122284
http://dx.doi.org/10.1186/s13046-019-1232-x

Ejemplares similares