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Inhibition of RNA polymerase III transcription by Triptolide attenuates colorectal tumorigenesis

BACKGROUND: Upregulation of RNA polymerase (Pol) III products, including tRNAs and 5S rRNA, in tumor cells leads to enhanced protein synthesis and tumor formation, making it a potential target for cancer treatment. In this study, we evaluated the inhibition of Pol III transcription by triptolide and...

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Detalles Bibliográficos
Autores principales:	Liang, Xia, Xie, Renxiang, Su, Jinfeng, Ye, Bingqi, Wei, Saisai, Liang, Zhibing, Bai, Rongpan, Chen, Zhanghui, Li, Zhongxiang, Gao, Xiangwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533717/ https://www.ncbi.nlm.nih.gov/pubmed/31122284 http://dx.doi.org/10.1186/s13046-019-1232-x

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