Enhancing surfactin production by using systematic CRISPRi repression to screen amino acid biosynthesis genes in Bacillus subtilis

BACKGROUND: Surfactin is a cyclic lipopeptide that is of great industrial use owing to its extraordinary surfactant power and antimicrobial, antiviral, and antitumor activities. Surfactin is synthesized by a condensation reaction in microbes, which uses fatty acids and four kinds of amino acids (l-g...

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Detalles Bibliográficos
Autores principales: Wang, Congya, Cao, Yingxiu, Wang, Yongping, Sun, Liming, Song, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533722/
https://www.ncbi.nlm.nih.gov/pubmed/31122258
http://dx.doi.org/10.1186/s12934-019-1139-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533722/
https://www.ncbi.nlm.nih.gov/pubmed/31122258
http://dx.doi.org/10.1186/s12934-019-1139-4

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