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Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy

BACKGROUND: Skeletal muscle atrophy is a pathological condition that contributes to morbidity in a variety of conditions including denervation, cachexia, and aging. Muscle atrophy is characterized as decreased muscle fiber cross-sectional area and protein content due, in part, to the proteolytic act...

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Detalles Bibliográficos
Autores principales: Lala-Tabbert, Neena, Lejmi-Mrad, Rim, Timusk, Kristen, Fukano, Marina, Holbrook, Janelle, St-Jean, Martine, LaCasse, Eric C., Korneluk, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533726/
https://www.ncbi.nlm.nih.gov/pubmed/31126323
http://dx.doi.org/10.1186/s13395-019-0201-6