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Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus

BACKGROUND: Epigenetic mechanisms may play a major role in the biological embedding of early-life stress (ELS). One proposed mechanism is that glucocorticoid (GC) release following ELS exposure induces long-lasting alterations in DNA methylation (DNAm) of important regulatory genes of the stress res...

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Detalles Bibliográficos
Autores principales: Wiechmann, Tobias, Röh, Simone, Sauer, Susann, Czamara, Darina, Arloth, Janine, Ködel, Maik, Beintner, Madita, Knop, Lisanne, Menke, Andreas, Binder, Elisabeth B., Provençal, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533766/
https://www.ncbi.nlm.nih.gov/pubmed/31122292
http://dx.doi.org/10.1186/s13148-019-0682-5